Human Organs From Pigs — But You’d Have to Kill One to Get One.


What if we could end the organ shortage tomorrow and everyone on the list could get a transplant within a few weeks?  Would you be willing to endorse this new source of organs?  If the source were a pig would you be willing to kill it to save your own life?

Xenotransplantation is the process of transplanting organs from animals into humans and historically that hasn’t worked too well. The human immune system immediately and violently attacks organs from animals and even our most powerful immunosuppressant drugs are ineffective but scientists are working on the problem because if we could use animal organs (ethical questions aside for now) we could end the organ shortage almost immediately.

The answer may lie in raising transgenic animals – animals that carry genes from other species or in the case of humans, animals that have been genetically modified so that their organs are transplantable into human beings.

According to www.actionbioscience.org  Transgenic animals are not a pipe dream either, they are already being produced.  The majority has been mice but scientists have also produced rabbits, pigs, sheep, and cattle. The primary question is not if we can raise pigs to produce organs for humans but when that is likely to happen and it’s possible it could happen relatively soon.  In Korea scientists have already cloned a genetically altered pig with hopes of using its organs in humans but that has, to my knowledge, not yet been done successfully.

There are distinct medical applications to the process of transgenics and providing a ready supply of transplantable organs is one of them.  Presently there is a single protein that can cause rejection but researchers think they can eliminate that problem in the not too distant future by replacing it with a human protein.  It is also possible that animals could be raised to be disease resistant which would benefit both the animal and humans to which some animal diseases can cross.

Pigs are currently thought to be the best candidates for organ donation. The risk of cross-species disease transmission is decreased because of their increased phylogenetic distance from humans. They are readily available, their organs are anatomically comparable in size, and new infectious agents are less likely since they have been in close contact with humans through domestication for many generations.

Aside from growing organs for transplantation, milk producing animals are desirable, too, because they can be used to producenutritional supplements and pharmaceuticals.   Products such as insulin, growth hormone, and blood anti-clotting factors may soon be or have already been obtained from the milk of transgenic cows, sheep, or goats. Research is also underway to manufacture milk through transgenesis for treatment of debilitating diseases such as phenylketonuria (PKU), hereditary emphysema, and cystic fibrosis.

So, yes, there are great possibilities with transgenic animals but there are also ethical concerns that must be addressed.  For example:

  • Should there be universal protocols for transgenesis?
  • Should such protocols demand that only the most promising research be permitted?
  • Is human welfare the only consideration? What about the welfare of other life forms?
  • Should scientists focus on in vitro (cultured in a lab) transgenic methods rather than, or before, using live animals to alleviate animal suffering?
  • Will transgenic animals radically change the direction of evolution, which may result in drastic consequences for nature and humans alike?
  • Should patents be allowed on transgenic animals, which may hamper the free exchange of scientific research?

Animals like pigs offer hope for the thousands of people languishing on the national transplant list.  Unfortunately these things take time and while scientists and then politicians and bureaucrats investigate the possibilities thousands will die waiting for organs.  The altruistic system that we have in place in America just isn’t enough.  We must do more to save the lives of those who need organs.  Hope lies in xenotransplantation, regenerative medicine, therapeutic cloning and artificial organ development.  We must keep that hope alive by support these efforts.

Bob Aronson of Bob’s Newheart is a 2007 heart transplant recipient, the founder of Facebook’s nearly 2,500 member Organ Transplant Initiative and the author of most of these donation/transplantation blogs.

You may comment in the space provided or email your thoughts to me at bob@baronson.org. And – please spread the word about the immediate need for more organ donors. There is nothing you can do that is of greater importance. If you convince one person to be an organ and tissue donor you may save or positively affect over 60 lives. Some of those lives may be people you know and love.

Please view our video “Thank You From the Bottom of my Donor’s heart” on http://www.organti.org This video was produced to promote organ donation so it is free and no permission is needed for its use.

If you want to spread the word personally about organ donation, we have another PowerPoint slide show for your use free and without permission. Just go to http://www.organti.org and click on “Life Pass It On” on the left side of the screen and then just follow the directions. This is NOT a stand-alone show; it needs a presenter but is professionally produced and factually sound. If you decide to use the show I will send you a free copy of my e-book, “How to Get a Standing “O” that will help you with presentation skills. Just write to bob@baronson.org and usually you will get a copy the same day.

Also…there is more information on this blog site about other donation/transplantation issues. Additionally we would love to have you join our Facebook group, Organ Transplant Initiative The more members we get the greater our clout with decision makers.

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About Bob Aronson

About Bob Aronson On August 21, 2007 I received a new heart at the Mayo Clinic in Jacksonville, Florida. All these years later I am very active, happy and loving life. God bless my donor and his family. His generosity toward a complete stranger will never be forgotten. I am retired and live with my wife Robin and two dogs Reilly the main dog and Ziggy the backup. We are a very happy family. My gratitude to my wonderful caregiver wife, my donor, his family and the Mayo Clinic is beyond my ability to express. Suffice it to say I will do whatever is in my power to promote organ and tissue donation and to help and support everyone affected by the issue. As a result of receiving the “Gift of Life” I have made a major commitment to organ/tissue/blood donation, transplantation and related issues. I am the founder of Facebook's over 4,000 member support group, Organ Transplant Initiative (OTI) and the blog site, “Bob’s Newheart” www.bobsnweheart.wordpress.com. I have authored the great majority of the nearly 250 blogs listed there. The remainder were written by excellent guest bloggers. The posts span a wide variety of topics mostly involving organ/tissue donation/transplantation and related issues, but also covering important current medical news and information. Wordpress data indicate the blogs have readers in 162 countries. Bob's Newheart is quickly becoming the news and information source of choice for those with an interest in organ/tissue donation/transplantation along with current developments in medical news and health care. Born In Chisholm, Minnesota I now reside in Jacksonville, Florida. I have three children and one step son, 8 grandchildren and 3 great grandchildren. My three grown children are Roger Aronson a well-known and respected Minneapolis, Minnesota Attorney, Dr. Colleen Hegranes Senior Vice President St. Catherine University in St. Paul, Minnesota and Harryet (Hank) Freeman who is probably the best history teacher in America, at least that's what her students at Woodbury, Minnesota High school tell me. Stepson Tim Grant and wife Jennifer live a couple of blocks from us in Jacksonville. Jen is a talented cook, baker, and mother. Tim is an in-demand electrician in Jacksonville who can really make almost anything work. Stella and Lily Grant are two very bright and talented granddaughters. For 25 plus years I owned the Aronson Communications Group an international consultancy specializing in health care communication. The Mayo Clinic was my first consulting client, a relationship that lasted until my retirement. I also worked with 3M health care, UNOS, LIfeSource, Dartmouth University Medical Center and CH2M HILL, one of the nation's largest environmental engineering firms. Prior to being a consultant I served for four years as the first Anchor for Morning Edition on the Minnesota Public Radio Network; was the Communications director for Minnesota Governor Rudy Perpich and before that held positions as a broadcast journalist at several Midwest facilities. I also served as the Director of broadcast communications at Moorhead State University in Moorhead, Minnesota. While I am retired Robin is not and I assist her efforts as founder and owner of Jingler’s Jewelry. She designs and makes colorful, "Fun" anodized aluminum jewelry and is also an accomplished printmaker. She sells her creations at art shows, festivals and gift shops in states east of the Mississippi but mostly in the south. Her website is www.jinglersjewelry.com. When I have time, my hobbies include reading, music and woodworking. One of my most notable projects was completing a wood scale model of the mom and pop grocery store my parents ran for 50 years in Chisholm, Minnesota. The model now resides in Chisholm in my sister's home. Our parents were wonderful people who instilled in us a very strong work ethic and a sense of fairness and equality. I also built a dollhouse for granddaughter Lily Grant and just completed designing and building a CD box that looks like an accordion. A friend commissioned me to make it in memory of his father who was an accomplished accordion musician. I have a brother and sister of whom I am very proud . They are twins. Terry is a Minnesota District Court Judge and Mary a retired but still the best 3rd grade teacher in America. I am proud of them for what they have done but more importantly for who they are. My wife Robin is a caregiver, musician, artist, entrepreneur and the best friend I have. While we do a lot of things together we especially like making music. Often in the evening you can hear the strains of folk, Blue Grass, country and other music coming from our family room. Robin plays several instruments including string bass, accordion, guitar, ukulele, mandolin and...well the list goes on. I play harmonica and have one in almost every key. She's really good...I'm not. Quantity does not ensure quality. One more thing. I am also a recovering Alcoholic and a former smoker. I emerged from a 28 day in-patient alcoholism treatment program in August of 1982 and have managed to stay sober with the help of a lot of people both in and out of Alcoholics Anonymous. I quit smoking in January of 1991 after a 37 year habit of up to four packs of cigarettes a day. It wasn’t easy but I’m living proof that it can be done. I am available to anyone suffering from or affected by any addiction at any time through my email address bob@baronson.org or via phone 904-434-6512.

Posted on August 24, 2012, in Xenotransplantation and tagged , , , , , , , , , , , , , , , . Bookmark the permalink. 2 Comments.

  1. It is only an ethical dilemma if you are empathetic and do not lack the ability to understand that other animals deserve to enjoy life as well Debra.

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  2. Debra Weathers

    I would love to know how many people on the transplant list would say no to killing a pig if it was going to save their owm life. I don’t see that as much of an ethical dilemma at all. I enjoy eating bacon, I think I would enjoy life even more. Thank you for the blog.

    Like

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